Colistin sulphate

Colistin Sulphate – Veterinary Antibiotic for Gut Infections

1. Introduction

Colistin Sulphate is a polymyxin-class antibiotic effective against gram-negative bacteria such as E. coli, Salmonella, and Pseudomonas. It is widely used in veterinary medicine to treat diarrhea, enteritis, and gastrointestinal infections in livestock and aquaculture.

2. Applications in veterinary medicine

2.1 Treatment of diarrhea and enteritis

• Highly effective against E. coli, the main cause of diarrhea in piglets, calves, and poultry

• Used in acute intestinal infections and dehydration cases

2.2 Used in oral powders, premixes, and injectables

• Colistin Sulphate is formulated in soluble powders, feed premixes, and injectable solutions

• Can be combined with other antibiotics like Amoxicillin, Neomycin for synergistic effects

2.3 Preventive applications

• Low-dose use for routine prevention in poultry, piglets, and aquaculture

• Improves survival rates and growth performance

3. Key advantages

• Acts locally in the gut, low systemic absorption → high safety

• Potent antibiotic, effective even at low doses

• Low resistance when used appropriately

• Water-soluble powder, easy to mix and formulate

4. Product information

• Name: Colistin Sulphate

• Form: White to off-white powder

• Purity: ≥ 98% (Potency ~20 million IU/g)

• Standards: USP / BP / EP

• Origin: China / India

• Storage: Store in a cool, dry place, keep container tightly closed

 

5. Conclusion

Colistin Sulphate is a powerful and targeted antibiotic for treating gut infections caused by gram-negative bacteria. It offers fast action, high safety, and is ideal for both treatment and prevention in modern animal production systems.