N,N-Dimethylacetamide (DMAC)

N,N-Dimethylacetamide (DMAC) – Veterinary-Grade Solvent for Injectable Formulations

1. Introduction

N,N-Dimethylacetamide (DMAC) is a highly polar, low-volatility solvent ideal for dissolving poorly soluble active ingredients in veterinary injectable, oral, and topical formulations.

In animal health, DMAC enhances drug solubility, formulation stability, and bioavailability, especially in injectable solutions containing antibiotics, antiparasitics, and anti-inflammatories.

2. Veterinary Applications

2.1 Solvent for Injectable Drugs

• Solubilizes compounds like ivermectin, albendazole, enrofloxacin, oxytetracycline, etc.

• Prevents crystallization and phase separation in long-term storage

2.2 Enhances Drug Absorption

• Improves transdermal and mucosal penetration of active substances

• Maintains homogeneity in injectable or topical veterinary preparations

2.3 Carrier in Disinfectants

• Used as a solvent base in organic disinfectants and esters

• Enhances spreadability and antimicrobial effectiveness

3. Key Benefits

• Clear, odorless solvent with low moisture content

• Compatible with many active ingredients and co-solvents (ethanol, PEG, PG)

• Suitable for R&D and industrial veterinary manufacturing

4. Product Specifications

• Name: N,N-Dimethylacetamide (DMAC)

• Appearance: Transparent, colorless liquid

• Packaging: 200 L drum or ISO tank

• Origin: China / Korea / India

• Storage: Sealed, cool, well-ventilated area away from flames

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5. Safety & Warnings

• May cause irritation upon long exposure

• For industrial veterinary use only – not for direct animal contact

• Use PPE: gloves, safety glasses, mask when handling

6 . Conclusion

DMAC is a trusted and essential high-performance solvent in the veterinary pharmaceutical industry, enabling stable and effective drug delivery for livestock and pets alike.